EXTRA-Meso (EXercise TheRApy in Mesothelioma) Feasibility

The goal of this clinical trial is to learn whether running an exercise study in patients with mesothelioma is feasible. The main question(s) it aims to answer are: 1. Is it feasible to recruit patients to a randomised clinical trial of exercise therapy 2. What are the barriers to study recruitment 3. What are the barriers to study retention Participants who decide to take part in the study will be randomly allocated one of two study arms: 1. Standard of care, where the participant will undergo their usual clinical follow-up 2. Exercise therapy, where the participant will receive a personalised 12 week exercise, nutrition and wellbeing programme Participants in both study arms will be asked to complete quality of life questionnaires and a basic fitness assessment at the start and end of the study follow-up period. Participants will be asked if they would be happy to conduct a short interview with a member of the research team, to assess their views on the study. This interview will be audio recorded and the audio recording will be transcribed anonymously to allow researchers to improve future study design.

NCT Number	NCT06491784
Lead Sponsor	NHS Greater Glasgow and Clyde Collaborators: University of Surrey, Manchester University NHS Foundation Trust, Mesothelioma UK
Conditions	Mesothelioma
Enrollment	40 participants
Start Date	2024-01-25
Primary Completion	2025-01-31 (estimated)
Study Completion	2025-07-31 (estimated)
Updated on ClinicalTrials.gov	2024-07-09