Effect of Aerobic Interval Training on Atrial Fibrillation Burden

Atrial fibrillation is the most common arrhythmia, with an increasing incidence and prevalence, significantly increasing the risk of death, stroke, heart failure, cognitive impairment, and dementia, severely impacting the quality of life for patients and burdening society and healthcare systems. In recent years, exercise-based cardiac rehabilitation has gradually become a new approach for the treatment of patients with heart disease. The main research topics include: 1. Changes in atrial fibrillation burden in non-permanent atrial fibrillation patients after 12 weeks of HIIT(high-intensity interval training ) or MIIT (moderate-intensity interval training). 2. Changes in cardiorespiratory fitness, quality of life scores, mental health assessment scores, atrial strain, and left ventricular diastolic function in non-permanent atrial fibrillation patients after 12 weeks of aerobic interval training, along with follow-up on the occurrence of exercise-related adverse events and adverse cardiovascular events during the study period.

NCT Number	NCT06491329
Lead Sponsor	Navy General Hospital, Beijing
Conditions	Atrial Fibrillation, Cardiac Rehabilitation
Enrollment	156 participants
Start Date	2024-08-15
Primary Completion	2027-07-15 (estimated)
Study Completion	2028-07-30 (estimated)
Updated on ClinicalTrials.gov	2024-08-02