Left Bundle Branch Area Pacing in Patients With Heart Failure

The relevance of Left Bundle Branch Pacing (LBBP) lies in its potential as a promising treatment option for patients with heart failure and left bundle branch block. LBBP aims to restore the normal physiological activation of the heart by delivering electrical impulses to the anatomical area of the left bundle branch, which may lead to more effective and synchronized ventricular contractions. Compared to traditional cardiac resynchronization therapy (CRT), this can result in a more physiological correction of dyssynchrony, improvement in left ventricular pump function, reduction in left ventricular volumes, and a decrease in mitral regurgitation. A crucial criterion is the reduction of heart failure symptoms and the enhancement of the patients quality of life.

NCT Number	NCT06488989
Lead Sponsor	National Research Center for Cardiac Surgery, Kazakhstan
Conditions	Heart Failure With Reduced Ejection Fraction, Left Bundle Branch Area Pacing, Heart Failure, Cardiac Resynchronization Therapy, Cardiac Resynchronization Therapy Devices, Conduction System Pacing, Left Bundle-Branch Block
Enrollment	50 participants
Start Date	2024-06-01
Primary Completion	2025-06-01 (estimated)
Study Completion	2026-06-01 (estimated)
Updated on ClinicalTrials.gov	2024-07-05