Clinical Trial

Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery

Recruiting Phase 2
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Summary
The goal of this clinical trial is to see if pantoprazole (a proton pump inhibitor used for acid reflux/heart burn) can reduce nausea and vomiting after gynecologic surgery in women between the ages of 18 and 79. Researchers will compare a placebo to the active medication. Participants will be asked to take three pills around their surgery, two taken before and one taken the night after.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-06-28; most recent amendment 2025-05-16.
Trial Details
NCT Number NCT06488001
Lead Sponsor United States Naval Medical Center, Portsmouth
Conditions Postoperative Nausea and Vomiting
Enrollment 132 participants
Start Date 2022-08-26
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2025-05-21