Clinical Trial

Compare the Efficacy and Outcome Between Fentanyl and Morphine as Analgo-sedation in Mechanically Ventilated Patients

Recruiting Phase 4
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Record status
This record was last updated October 6, 2025 (before its estimated November 15, 2025 completion). Its status may not reflect the trial's current state.
Summary
The primary aim of this clinical trial is to compare the effectiveness of fentanyl vs morphine as analgosedation in mechanically ventilated adult patients in the ICU. This study also aims to compare the outcomes of patients between the two groups. The main questions it aims to answer are : 1. Does propofol and fentanyl infusion as analgo-sedation achieve targeted sedation score at 12 and 24 hours compared to propofol and morphine infusion in mechanically ventilated adult patients in the intensive care unit (ICU)? 2. Is there a difference between the proportion of patients requiring rescue sedation dose between the fentanyl and morphine groups?
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-06-27.
Status change: Not Yet Recruiting → Recruiting 2025-09-30
Trial Details
NCT Number NCT06479655
Lead Sponsor Universiti Sains Malaysia
Conditions Effect of Drug
Enrollment 116 participants
Start Date 2024-07-15
Primary Completion 2025-11-15 (estimated)
Study Completion 2025-12-30 (estimated)
Updated on ClinicalTrials.gov 2025-10-06