Efficacy of SGLT2 Inhibitors in Adults With Sepsis

Goal of this clinical trial is to examine the safety and efficacy of SGLT2 inhibitors on the clinical outcomes in patients with sepsis. Main study outcomes are as follows: (i) Primary objective is to examine the efficacy and safety of SGLT2 inhibitors on clinical outcomes in patients with sepsis. (ii) Secondary objective is to examine the effect of SGLT2 inhibitors on inflammatory markers in patients with sepsis.

NCT Number	NCT06473844
Lead Sponsor	Hospital Authority, Hong Kong Collaborators: Chinese University of Hong Kong
Conditions	Sepsis, Inflammation, SGLT2 Inhibitors, Critically Ill, Organ Dysfunction Syndrome
Enrollment	60 participants
Start Date	2025-03-05
Primary Completion	2027-02-28 (estimated)
Study Completion	2027-02-28 (estimated)
Updated on ClinicalTrials.gov	2025-03-19