Biomarkers After Out-of-hospital Cardiac Arrest- a STEPCARE Substudy

A prospective multicenter biomarker study with adult patients treated on intensive care units after out-of-hospital cardiac arrest. Patients will be recruited from specific sites participating in the Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation (STEPCARE) trial. (ClinicalTrials.gov ID NCT05564754). Blood samples will be collected at 12, 24, 48, and 72 hours after randomization in selected sites, aliquoted and frozen on-site. After trial completion, samples will be stored in a central biobank. Sample analysis will be performed in batch after trial completion. Functional outcome will be assessed at 30 days and 6 months after cardiac arrest.

NCT Number	NCT06471972
Lead Sponsor	Region Skane Collaborators: University of Helsinki, The George Institute, Copenhagen Trial Unit, Center for Clinical Intervention Research, Medical Research Institute of New Zealand
Conditions	Cardiac Arrest
Enrollment	1,000 participants
Start Date	2023-10-01
Primary Completion	2027-12-31 (estimated)
Study Completion	2029-12-31 (estimated)
Updated on ClinicalTrials.gov	2024-09-19