Clinical Trial

Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases

Study acronym: PDO
Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated December 22, 2025 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The aim of the study is to generate patient-derived organoids (PDOs) from brain resection or biopsied extra-cranial metastases. The preliminary data collected will be used to assess the ability of PDOs to predict patients' treatment response and their radio-sensitivity and chemo-sensitivity can be correlated with their survival outcome.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-06-18.
Status change: Not Yet Recruiting → Recruiting 2025-12-15
Trial Details
NCT Number NCT06468124
Lead Sponsor King's College London
Conditions Breast Neoplasms
Enrollment 20 participants
Start Date 2025-05-27
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2025-12-22