Clinical Trial

Methylphenidate in KBG Syndrome: N-of-1 Series

Study acronym: KBGS_N_of_1
Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial\] is to learn about the effect of methylphenidate in children and adolescents with KBG syndrome. The main question it aims to answer is: • What is the effectiveness of methylphenidate on attention deficit and ADHD-related symptoms in children and adolescents with KBG syndrome? Participants will receive multiple blocks of treatment with methylphenidate and placebo and fill out various questionnaires.
Protocol Amendment History 2 changes
notable Primary completion pushed: 2027-01-01 -> 2028-01-01 2026-08-12
minor Completion pushed: 2027-10-01 -> 2028-10-01 2026-08-12
Trial Details
NCT Number NCT06465641
Lead Sponsor Radboud University Medical Center
Conditions Kbg Syndrome, ADHD - Combined Type
Enrollment 15 participants
Start Date 2024-11-13
Primary Completion 2028-01-01 (estimated)
Study Completion 2028-10-01 (estimated)
Updated on ClinicalTrials.gov 2026-08-11