Bupivacaine and Epinephrine Injection Study

Endoscopic sinus surgery (ESS) is a common otolaryngologic procedure that aims to remove the partitions that separate the sinus cavities, remove inflamed tissue, and optimize the sinuses for topical medication use. In this procedure, the surgeon will inject a combination of drugs, local anesthetics, and vasoconstrictors, to reduce bleeding and improve visualization. However, previous studies have shown similar results when injected with only saline. In this study, investigators want to determine if the injection of local anesthesic+vasoconstrictor compared to no injection at all makes any difference in improving the surgeon's visualization during an ESS.

NCT Number	NCT06456255
Lead Sponsor	Amin Javer
Conditions	Sinus Disease, Anesthesia, Bleeding
Enrollment	80 participants
Start Date	2024-11-15
Primary Completion	2025-05 (estimated)
Study Completion	2025-07 (estimated)
Updated on ClinicalTrials.gov	2025-05-15