Clinical Trial

Changes in Eye Shape With Myopia Management Interventions

Active, Not Recruiting Phase 4
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Record status
This record was last updated January 27, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The goal of this clinical trial is to study changes in eye shape of nearsighted young adults using low-dose atropine eye drops or soft multifocal contact lenses. The main questions it aims to answer are: * do low-dose atropine and soft multifocal contact lenses affect the shape of the peripheral eye? * are changes in peripheral eye shape from these interventions influenced by changes in the focusing system of the eye? Participants will: * have multiple different types of photos taken * have their prescription for glasses/contacts checked * have their eye health checked, including the use of dilating eye drops * be randomly assigned to use eye drops every night or wear special contact lenses daily instead of their typical contacts * will complete five study visits over the course of 12 months Researchers will compare young adults using low-dose atropine to those wearing soft multifocal contact lenses and to those using no intervention to see if using these interventions affects retinal shape.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-06-04; most recent amendment 2026-01-26.
Status change: Recruiting → Active, Not Recruiting 2026-01-26
Status change: Not Yet Recruiting → Recruiting 2024-10-29
Trial Details
NCT Number NCT06450132
Lead Sponsor Ohio State University
Conditions Myopia
Enrollment 75 participants
Start Date 2024-08-01
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-07-31 (estimated)
Updated on ClinicalTrials.gov 2026-01-27