Clinical Trial

Prevention of Progression of Prediabetes, Obesity and CV Risk

Study acronym: Pre-DM

Recruiting Phase 1

Summary

The investigators are studying how to help people with prediabetes (Pre-DM) and obesity. The goal is to use new and affordable treatments to bring blood sugar levels back to normal and help participants to lose weight. The investigators also want to reduce participants risk of heart problems. The study team will look at how these treatments affect metabolism and other body functions to help find new ways to treat diabetes and obesity in the future.

Protocol Amendment History 3 amendments

This ClinicalTrials.gov record has been amended 3 times since 2024-05-31; most recent amendment 2025-11-10.

Trial Details

NCT Number	NCT06446531
Lead Sponsor	The University of Texas Health Science Center at San Antonio Collaborators: Baptist Health Foundation of San Antonio
Conditions	Pre-Diabetes, Weight, Body, Cardiovascular Diseases
Enrollment	64 participants
Start Date	2024-09-11
Primary Completion	2027-07 (estimated)
Study Completion	2027-07 (estimated)
Updated on ClinicalTrials.gov	2025-11-12