Clinical Trial

Investigating the Insulin Resistance in Individuals With Type 2 Diabetes

Recruiting
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Record status
This record was last updated September 19, 2024 (before its estimated December 31, 2024 completion). Its status may not reflect the trial's current state.
Summary
Numerous studies have provided evidence of a correlation between Type 2 Diabetes Mellitus (T2DM) and cognitive dysfunction, specifically in the realms of complex attention, information processing, and executive function. These impairments have been observed in middle-aged and elderly individuals with T2DM, with longer diabetes duration, suboptimal glycemic control, and the presence of diabetic complications being contributing factors. Recent research in young adults and adolescents diagnosed with T2DM has revealed cognitive and brain structural alterations in this growing demographic, suggesting that early disease mechanisms, rather than solely vascular and age-related neurodegeneration, contribute to pathogenesis. However, there remains uncertainty regarding the interplay between central and peripheral insulin resistance and its impact on cognitive dysfunction in individuals with T2DM. This study aims to investigate central insulin resistance in T2DM, elucidating its association with peripheral insulin resistance and the effects on cognitive impairments.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-05-20.
Status change: Not Yet Recruiting → Recruiting 2024-09-09
Trial Details
NCT Number NCT06428968
Lead Sponsor Central South University
Conditions Type 2 Diabetes
Enrollment 30 participants
Start Date 2024-09-06
Primary Completion 2024-12-31 (estimated)
Study Completion 2025-06-30 (estimated)
Updated on ClinicalTrials.gov 2024-09-19