Adiposity and Iron Requirements in Pregnancy

This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy. We will conduct a double-blind randomized controlled intervention study involving 312 pregnant women recruited from antenatal clinics in the Northern Trust Area. Participants will be randomly assigned to receive either 25 or 50 mg of iron per day from 12 weeks of pregnancy until delivery, using the Active Iron supplement brand. Blood samples will be collected at 12, 28 and 36 weeks gestation and umbilical cord blood will be collected at delivery. Anthropometric measurements will be taken at each visit, and participants will complete questionnaires on various aspects of health and lifestyle, mental health, gastrointestinal symptoms, and compliance.

NCT Number	NCT06425796
Lead Sponsor	University of Ulster Collaborators: Solvotrin Therapeutics - Active Iron, National Health Service, United Kingdom
Conditions	Iron Deficiency Anemia of Pregnancy
Enrollment	312 participants
Start Date	2024-05-20
Primary Completion	2027-01-19 (estimated)
Study Completion	2027-03-19 (estimated)
Updated on ClinicalTrials.gov	2026-07-01