Clinical Trial

Ketamine HCl Prolonged Release Oral Tablets for CRPS

Suspended Phase 2
View on ClinicalTrials.gov →
Why the trial stopped
Difficulty clearing through the FDA
Summary
The purpose of this study is to evaluate the efficacy of Ketamine HCl Prolonged Release (PR) tablets in participants with pain due to complex regional pain syndrome (CRPS). Additionally, this trial will explore the feasibility of the trial design through dosing compliance, clinical instruments for safety and quality of life measurements, and pharmacokinetic profile.
Protocol Amendment History 4 changes
critical Trial status changed: Not Yet Recruiting → Suspended 2026-07-28
critical Recruitment suspended: Difficulty clearing through the FDA 2026-07-28
notable Primary completion pushed: 2028-01 -> 2029-01 2026-07-28
minor Completion pushed: 2028-07 -> 2029-07 2026-07-28
Trial Details
NCT Number NCT06419985
Lead Sponsor University of Southern California
Conditions Complex Regional Pain Syndromes
Enrollment 65 participants
Start Date 2027-01
Primary Completion 2029-01 (estimated)
Study Completion 2029-07 (estimated)
Updated on ClinicalTrials.gov 2026-07-27