A Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated NSCLC

There are limited in depth studies on the epidemiology and clinical management of EGFR exon 20 insertion mutated NSCLC in Asia. In addition, there is preliminary data suggesting the exact location of the insertion and variant may influence the response and efficacy to novel EGFR targeted therapies. This study aims to fill this knowledge gap, by comprehensively characterising the epidemiology and clinical outcomes of Asian advanced EGFR exon 20 insertion mutated NSCLC patients.

NCT Number	NCT06418412
Lead Sponsor	National Cancer Centre, Singapore
Conditions	Advanced EGFR Exon 20 Insertion Mutated Non-Small Cell Lung Cancer
Enrollment	600 participants
Start Date	2024-03-15
Primary Completion	2026-12-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-06-12