Chronic Lung Allograft Dysfunction MRI Study

This studies purpose is to confirm the efficacy and efficiency of using OE-MRI and MRI with hyperpolarized gas techniques and Iodinated contrast CT scan, this will enhance understanding of CLAD pathophysiology. Moreover, this project is foundational to performing additional studies to establish if novel MRI imaging can serve as an objective confirmatory diagnostic tool for CLAD in post-transplant patients.

NCT Number	NCT06406777
Lead Sponsor	Sean Fain
Conditions	Chronic Lung Allograft Dysfunction Lung MRI (CLAD)
Enrollment	100 participants
Start Date	2025-03-20
Primary Completion	2028-09 (estimated)
Study Completion	2028-09 (estimated)
Updated on ClinicalTrials.gov	2026-08-06