Clinical Trial

RVU120 in Patients With Intermediate or High-risk, Primary or Secondary Myelofibrosis

Study acronym: POTAMI-61
Recruiting Phase 2
View on ClinicalTrials.gov →
Record status
This record was last updated September 23, 2025 (before its estimated June 2026 completion). Its status may not reflect the trial's current state.
Summary
The objective of this clinical trial is to evaluate the efficacy (how well the drug works), safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the study drug, RVU120, in treating adult patients with intermediate or high-risk, primary or secondary myelofibrosis. RVU120 will be given as a single agent or in combination with ruxolitinib.
Protocol Amendment History 10 amendments
This ClinicalTrials.gov record has been amended 10 times since 2024-04-29; most recent amendment 2025-09-22.
Status change: Not Yet Recruiting → Recruiting 2024-09-30
Trial Details
NCT Number NCT06397313
Lead Sponsor Ryvu Therapeutics SA
Conditions Myelofibrosis
Enrollment 230 participants
Start Date 2024-09-19
Primary Completion 2026-06 (estimated)
Study Completion 2027-10 (estimated)
Updated on ClinicalTrials.gov 2025-09-23