Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology

GynRAN is an international, multicentre, transversal, diagnostic and non-interventional study carried out in gynecology-obstetrics/gynecological oncology departments that aims to identify a diagnostic signature for gynecological pathologies by analyzing of coding and non-coding RNA contained in patients saliva. The study population consists of patients with clinically symptomatic females with one or more of the gynecological pathologies (endometriosis, adenomyosis, ovarian cysts, fibroids, ovarian/cervical/uterine cancer) and asymptomatic females. The patients concerned by the study will be managed without modification of the care pathway, nor modification of the therapeutic indications, nor modification of the diagnostic or follow-up examinations necessary according to the context, which are carried out according to the local recommendations.

NCT Number	NCT06392997
Lead Sponsor	ZIWIG Collaborators: Monitoring Force Group
Conditions	Gynecologic Disease, Gynecologic Cancer, Endometriosis, Ovarian Cancer, Cyst Ovary, Fibroid, Cervical Cancer, Uterine Cancer
Enrollment	2,500 participants
Start Date	2024-12-05
Primary Completion	2026-12 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2025-01-23