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Nationwide Research on the Rewilding of Kindergarten Yards

Study acronym: Vahvistu
StatusRecruiting
PhaseNot applicable
Started
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Record History

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  1. Start date changed from estimate of May 1, 2024 to May 15, 2024
    • Interventions: Biodiversity (Biological), Playground equipment (Other) to Biodiversity (Other), Playground equipment (Other)
    • Secondary endpoints revised (14)
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Biodiversity is essential for nature and human well-being. Land use has reduced biodiversity in cities that is associated with altered commensal microbiota and a rising burden of immunological disorders among urban children. The investigators will estimate how rewilding of kindergarten yards affects commensal microbiome, prevalence of allergies, asthma, atopic dermatitis and infections, cortisol levels, cognitive skills and plasma cytokine levels of children. Our specific aims are: To assess if rewilding diversifies health-associated skin, saliva and gut microbiota and reduces infectious diseases and atopic or allergic symptoms. Assess whether the rewilding has positive effects on cognitive skills. Assess whether the rewilding changes cortisol and plasma cytokine levels. The investigators will recruit altogether 320 (160 per treatment) study subjects aged between 1-5 to questionnaire study (Task 2), from which 120 study subjects will be analyzed more detailed using microbiological and blood samples (Task 1).
Trial Details
NCT Number NCT06390878
Lead Sponsor Natural Resources Institute Finland
Collaborators: Tampere University
Conditions
(from sponsor)		 Microbial Colonization, Atopic Dermatitis, Asthma in Children, Allergy, Cognitive Change, Respiratory Infection, Nature, Human
Related terms Communicable Diseases, Dermatitis, Atopic, Hypersensitivity, Respiratory Tract Infections
Enrollment 320 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov