Remote Tai Chi for Knee Osteoarthritis

The goal of this pragmatic randomized trial is to evaluate the effectiveness of remote Tai Chi to treat knee pain in adults with knee osteoarthritis. The main questions the trial aims to answer are: * Compared to routine care, will patients with Knee OA receiving remote Tai Chi exhibit greater improvement in knee-related pain (WOMAC pain score, primary outcome), pain interference (PROMIS-Pain Interference, secondary outcome), and health-related quality of life at 3 months? * Does remote tai chi decreases healthcare utilization and analgesic use over the one-year study period? Researchers will compare remote Tai Chi added to routine care to routine care alone to see if remote tai chi works to treat knee osteoarthritis pain. Participants will participate in remotely delivered web-based tai chi sessions, twice a week for 12 weeks, or will continue to receive routine care. Participants will be followed for 12 months after randomization.

NCT Number	NCT06384898
Lead Sponsor	Tufts Medical Center Collaborators: Boston Medical Center, University of California, Los Angeles, The Cleveland Clinic, National Center for Complementary and Integrative Health (NCCIH)
Conditions	Knee Osteoarthritis
Enrollment	480 participants
Start Date	2025-04-07
Primary Completion	2027-12-31 (estimated)
Study Completion	2028-08-31 (estimated)
Updated on ClinicalTrials.gov	2025-07-08