Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft

Investigators hypothesize that topical tranexamic acid will have better or comparable efficacy to topical thrombin in reducing hematoma formation at the wound base. The purpose of the study is to demonstrate that topical tranexamic acid will be a non-inferior alternative medication to the current standard of care,THROMBIN-JMI® , and at a lower cost to the health system.

NCT Number	NCT06379724
Lead Sponsor	University of Kansas Medical Center
Conditions	Burns, Skin Graft Complications
Enrollment	62 participants
Start Date	2024-07-11
Primary Completion	2026-12 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2025-10-20