Clinical Trial

ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia Repair

Study acronym: ALPINE
Recruiting
View on ClinicalTrials.gov →
Summary
This study investigates on the effect of two different operative techniques to treat abdominal wall hernias. The goal of this clinical trial is to learn if the eTEP (Extended totally extraperitoneal repair) technique leads to a better outcome than the IPOM (Intraperitoneal onlay mesh) technique. The main questions it aims to answer are: * pain after the operation * rate of complications * rate of recurrence and reoperations * quality of life. Participants will: Either be operated using the eTEP or the IPOM technique. Be followed up either in person or via email / phone call at day 1, day 7, day 14, 6 weeks, 6 months, 1, 3 and 5 years after the surgery to asses the above-stated main and some more outcomes.
Protocol Amendment History 2 changes
notable Primary completion pushed: 2025-12-31 -> 2026-12-31 2026-07-25
minor Completion pushed: 2030-12-31 -> 2031-12-31 2026-07-25
Trial Details
NCT Number NCT06367309
Lead Sponsor University Hospital, Basel, Switzerland
Collaborators: St. Clara Hospital, Basel, Switzerland, Innklinikum Altötting, Germany, Hôpital du Valais
Conditions Ventral Hernia, Abdominal Wall Defect
Enrollment 138 participants
Start Date 2024-07-01
Primary Completion 2026-12-31 (estimated)
Study Completion 2031-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-24