Clinical Trial

Multi-omics Characteristics and Prognosis of Idiopathic Sudden Sensorineural Hearing Loss

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Summary
The goal of this observational study is to describe the multi-omics characteristics and to learn about the prognostic factors in patients with idiopathic sudden sensorineural hearing loss (SSNHL). The main problems it aims to deal with are: * if there is a difference in data of exome and targeted sequencing among patients with SSNHL affecting bilateral and unilateral sides, and healthy controls * if there is a difference in the parameter of MRI among patients with SSNHL affecting bilateral and unilateral sides, and healthy controls * to find out which factor from multi-omics data relates to outcomes of SSNHL * to develop the best prognostics model based on the multi-omics data. Participants will be received audiological tests, blood specimen collection and radiological examination. Researchers will explore the relationship between the multi-omics data and the prognosis and develop the predictive model.
Trial Details
NCT Number NCT06365775
Lead Sponsor Dan Bing
Conditions Sudden Sensorineural Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Sudden
Enrollment 400 participants
Start Date 2024-04-23
Primary Completion 2026-11-23 (estimated)
Study Completion 2026-11-23 (estimated)
Updated on ClinicalTrials.gov 2024-04-15