Clinical Trial

oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias

Study acronym: PRIOR

Recruiting

Summary

This study investigates on the effect of two different operative techniques to treat large abdominal wall defects. The goal of this clinical trial is to learn if the minimally-invasive, robotically-assisted ventral hernia repair (RVHR) leads to a better outcome than the open ventral hernia repair (OVHR). The main questions it aims to answer are: length of stay after the operation rate of complications rate of recurrence and reoperations quality of life. Participants will: Either be operated using the RVHR or OVHR will be followed up either in person or via email / phone call at day 7, day 30, 6 months, 1, 3 and 5 years after the surgery to asses the above-stated main and some more outcomes.

Protocol Amendment History 4 changes

critical Recruitment opened 2026-07-25

notable Trial sites expanded: 0 -> 3 locations 2026-07-25

notable Primary completion pushed: 2027-12-31 -> 2028-12-31 2026-07-25

minor Completion pushed: 2031-12-31 -> 2033-12-31 2026-07-25

Trial Details

NCT Number	NCT06364306
Lead Sponsor	University Hospital, Basel, Switzerland Collaborators: St. Clara Hospital, Basel, Switzerland, Klinikum Kempten, Kempten, Germany, Hôpital du Valais
Conditions	Ventral Hernia, Incisional Hernia, Abdominal Wall Defect
Enrollment	140 participants
Start Date	2026-07-14
Primary Completion	2028-12-31 (estimated)
Study Completion	2033-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-24