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Radiotherapy vs Catheter Ablation for Ventricular Tachycardia in Structural Heart Disease

Study acronym: RadioAblate-VT
StatusRecruiting
PhaseNot applicable
Started2025-11-03
View on ClinicalTrials.gov ↗
Record status
This record was last updated February 18, 2026 (before its estimated June 20, 2026 completion). Its status may not reflect the trial's current state.

Amendment history

2026-02-15
Not Yet Recruiting→Recruiting Study Identification, Study Status, Contacts/Locations v2
Trial statusNot Yet Recruiting→Recruiting
Primary completion date2026-05-20→2026-06-20
Completion date2027-05-20→2027-12-20
Start dateestimated 2024-05-20→confirmed 2025-11-03
Study sites0→1
2024-04-29
Study Status, Outcome Measures v1
Primary completion date2026-04-15→2026-05-20
Completion date2027-04-15→2027-05-20
Start date2024-04-15→2024-05-20
2024-04-07
Original filing
The goal of this randomized clinical trial is to test the efficacy of stereotactic body radiation therapy (SBRT) in treating ventricular tachycardia (VT) in patients with advanced structural heart disease. The main questions it aims to answer are: * What is the efficacy of SBRT compared to catheter ablation (CA) in achieving a ≥ 75% reduction in VT burden at 6 months * What is the comparable safety profile of SBRT vs CA Researchers will compare SBRT and CA (standard of care).
Trial Details
NCT Number NCT06360939
Lead Sponsor Western Sydney Local Health District
Collaborators: University of Sydney, National Heart Foundation, Australia
Conditions Ventricular Tachycardia, Cardiomyopathies, Arrhythmias, Cardiac, Ventricular Arrythmia
Enrollment 60 participants
Start Date 2025-11-03
Primary Completion 2026-06-20 (estimated)
Study Completion 2027-12-20 (estimated)
Updated on ClinicalTrials.gov 2026-02-18