Syncope-Asystole Latency Time in Tilt Table Test: The SALT-TILT Study

Syncope is a common presenting condition. Pacemaker implantation can significantly reduce syncope recurrences in reflex syncope. However, despite careful selection, a substantial proportion of patients treated with pacemakers suffer recurrences of syncope. It is thought that a pronounced vasodepressor component may hinder the efficacy of pacing in patients, preventing adequate cerebral perfusion during the reflex, thus relativizing the anti-bradycardia function of the pacemaker to prevent syncope. It is hypothesised that the time elapsed from the actual loss of consciousness to the asystole recorded on the ECG during Tilt Table Test may be predictive in terms of response to pacemaker therapy, so this parameter becomes the subject of the present study.

NCT Number	NCT06356207
Lead Sponsor	Azienda Ospedaliera di Bolzano
Conditions	Syncope, Pacemaker, Asystole, Neurally Mediated Syncope
Enrollment	64 participants
Start Date	2024-03-20
Primary Completion	2026-03 (estimated)
Study Completion	2027-03 (estimated)
Updated on ClinicalTrials.gov	2024-04-11