Clinical Trial

Postop Pain Management in Pituitary Tumour Patients

Study acronym: POPPY

Recruiting Phase 4

Record status

This record was last updated March 12, 2026 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.

Summary

To assess the benefit of using an additional nerve block during minimally invasive pituitary surgery, to improve pain management after surgery. The medication (Bupivacaine) or a placebo (saline) will be injected during surgery and patients will be asked about their level of pain at multiple time points in the first 24 hours following surgery. Some patients will be randomized to a third, sham group that do not receive any additional injection. The aim is to improve patient outcomes and reduce the need for pain medication after surgery.

Protocol Amendment History 2 amendments

This ClinicalTrials.gov record has been amended 2 times since 2024-04-02; most recent amendment 2026-03-10.

Status change: Not Yet Recruiting → Recruiting 2025-03-14

Trial Details

NCT Number	NCT06353529
Lead Sponsor	Hamilton Health Sciences Corporation
Conditions	Pituitary, Pain, Postoperative
Enrollment	108 participants
Start Date	2024-11-25
Primary Completion	2026-04 (estimated)
Study Completion	2026-07 (estimated)
Updated on ClinicalTrials.gov	2026-03-12