Clinical Trial

Prediction of Propofol Effect-Site Concentration Associated With Deep Anesthesia

Study acronym: PRESCOD-AI
Recruiting
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Summary
The goal of this observational study is to explore the variability of the concentration at the effect site (Ce) of propofol to reach deep anesthesia (DA) during induction of general anesthesia in adults. The investigators hypothesized that there is a great variability in this Ce that could be precisely explained by * Electroencephalographic (EEG) features available prior to induction of anesthesia * Cognitive performance * Patients characteristics Participants will undergo preoperative cognitive testing and awake EEG. Then, induction of general anesthesia will be performed using continuous infusion of propofol. The Ce at which Deep anesthesia is observed will be recorded.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-03-28; most recent amendment 2026-01-15.
Status change: Not Yet Recruiting → Recruiting 2026-01-15
Trial Details
NCT Number NCT06346158
Lead Sponsor Ciusss de L'Est de l'Île de Montréal
Collaborators: Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Conditions Anesthesia
Enrollment 110 participants
Start Date 2025-04-07
Primary Completion 2027-01 (estimated)
Study Completion 2027-01 (estimated)
Updated on ClinicalTrials.gov 2026-01-16