Clinical Trial

A Clinical Trial to Investigate 18F-AzaFol in the Diagnosis of Large Vessel Vasculitis

Study acronym: CRAFT
Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The goal of this open-label clinical trial is to evaluate the efficacy of AzaFol-PET/CT in the diagnosis of GCA (giant cell arteritis), to compare AzaFol- with 2-\[18F\]FDG-PET/CT, and to assess the safety and tolerability of AzaFol in subjects with suspicion of GCA. Participants will undergo AzaFol-PET/CT imaging at a single timepoint.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2024-03-21; most recent amendment 2026-04-30.
Status change: Not Yet Recruiting → Recruiting 2025-01-08
Trial Details
NCT Number NCT06335888
Lead Sponsor Insel Gruppe AG, University Hospital Bern
Collaborators: Paul Scherrer Institut, Center for Proton Therapy
Conditions Giant Cell Arteritis
Enrollment 70 participants
Start Date 2025-02-03
Primary Completion 2029-05 (estimated)
Study Completion 2029-05 (estimated)
Updated on ClinicalTrials.gov 2026-05-01