Different Amounts of Moxibustion in the Treatment of DPN: A Clinical RCT Study

This study aims to provide moxibustion treatment for diabetic peripheral neuropathy (DPN) and a reference for clinical treatment of DPN moxibustion. Patients will be randomly assigned to 3 clinical centers, 30 in each center, and then equally divided into 3 groups, including a drug treatment group, a 15-minute moxibustion group, and a 30-minute moxibustion group. Patients in the drug treatment group were given mecobalamin tablets and epalrestat at the same time of daily treatment (hypertension and hyperlipidemia combined with basic drug treatment) for 4 weeks. The frequency of moxibustion was 15/30 minutes per acupoint twice a week for 4 weeks. The results were evaluated during the baseline period (the day before the grouping), the treatment period (the end of the 8th treatment), and the follow-up period (a month after the end of treatment). The results of this part are expected to confirm the therapeutic effect of moxibustion on diabetic peripheral neuropathy. The results of this part will be expected to confirm the optimal amount of moxibustion in the treatment of diabetic peripheral neuralgia and provide a reference for the standardization of clinical treatment of moxibustion.

NCT Number	NCT06330233
Lead Sponsor	Zhejiang Chinese Medical University Collaborators: The First Affiliated Hospital of Zhejiang Chinese Medical University, Zhejiang Greentown Cardiovascular Hospital
Conditions	Diabetic Peripheral Neuropathy, Pain, Moxibustion, Randomized Controlled Trial
Enrollment	90 participants
Start Date	2024-09-01
Primary Completion	2026-05-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-03-13