Cohort Study on Plant-based Diets (COPLANT Study)

The Cohort on Plant-based Diets (COPLANT) study is a multi-centre cohort study that starts baseline recruitment from 2024 to 2027 with approximately 6,000 participants in Germany and Austria. The COPLANT study focuses on vegan (no animal products), vegetarian (no meat and fish, but dairy products and eggs), pescetarian (no meat, but fish) and omnivorous (mixed diet including all possible animal products) diets. The aim of the COPLANT study is to gain new insights on health benefits and risks as well as social, ecological and economic effects of different plant-based diets in comparison to a mixed diet. In addition to a detailed dietary survey using an app adapted to the needs of this study, the baseline examination includes measurements of body composition, bone health, cardiovascular risk factors, diabetes risk, contaminants and lifestyle. For the basic laboratory program, fasting blood, 24-hour urine collection and a stool sample are taken from all study participants. Furthermore, specific aspects of dietary behavior, physical activity and other lifestyle factors are collected via questionnaires. Follow-up studies are planned at intervals of 5, 10 and 20 years after the baseline visit.

NCT Number	NCT06323538
Lead Sponsor	German Federal Institute for Risk Assessment Collaborators: Max Rubner-Institut, University of Bonn, Research Institute for Plant-Based Nutrition, University of Jena, University of Regensburg, Heidelberg University, University of Vienna
Conditions	Dietary Exposure, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Bone Loss, Sustainability, Exposure, Obesity, Vitamin Deficiency +1 more
Enrollment	6,000 participants
Start Date	2024-04-09
Primary Completion	2027-03-31 (estimated)
Study Completion	2047-03-31 (estimated)
Updated on ClinicalTrials.gov	2025-02-14