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Can Exercise Rewire the Brain Addiction Circuitry?

Study acronym: REWIRED
StatusNot Yet Recruiting
PhaseNot applicable
Started
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Record History

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  1. Start date: Jan 2025 to Jan 2026v3
  2. Interventions: Aerobic Exercise (Behavioral), Agility Exercise (Behavioral), Stretching/posture correction (Behavioral) to Aerobic Exercise (Behavioral), Agility-Cognitive Exercise (Behavioral), Stretching/relaxation (Behavioral)
    • Study description revised
    v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The aim of the present study is to apply neuroimaging techniques to investigate how physical exercise may influence the addiction circuitry, ultimately reducing alcohol consumption and craving in youth binge drinkers. This proposal will advance knowledge on how exercise may modulate the neurocircuitry of addiction. Uncovering the neurobiological mechanisms underlying the interactive neural effects of exercise and alcohol intake may provide additional scientific insights for the development of preventive and intervention programs for youth BD and AUD.
Trial Details
NCT Number NCT06317753
Lead Sponsor University of Minho
Conditions
(from sponsor)		 Physical Exercise
Related terms Binge Drinking, Motor Activity
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov