Clinical Trial

Intensive Weight Loss Intervention Versus Bariatric Surgery for Adults With Severe and Complex Obesity: the LightBAR Randomised Trial

Study acronym: LightBAR
Recruiting
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Summary
With this trial, the aim is to assess the benefits and harms of a non-surgical intensive weight loss intervention that includes total dietary replacements, behavioural support and weight-loss medication compared with bariatric surgery for people with severe and complex obesity. The interpretation of the results will help inform future care pathways for people with obesity in whom bariatric surgery is currently the only available effective treatment option.
Protocol Amendment History 13 amendments
This ClinicalTrials.gov record has been amended 13 times since 2024-03-06; most recent amendment 2026-02-09.
Status change: Not Yet Recruiting → Recruiting 2024-04-11
Trial Details
NCT Number NCT06309238
Lead Sponsor Carsten Dirksen
Collaborators: University of Copenhagen, University of Southern Denmark, University of Oxford, Copenhagen Trial Unit, Center for Clinical Intervention Research
Conditions Obesity
Enrollment 500 participants
Start Date 2024-05-08
Primary Completion 2027-12 (estimated)
Study Completion 2048-12 (estimated)
Updated on ClinicalTrials.gov 2026-02-11