Clinical Trial

An Antibiotic Protocol Guided by a Multimodal Approach in AECOPD With Pneumonia in Intensive Care

Study acronym: BPCTréa2
Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated July 24, 2025 (before its estimated April 15, 2026 completion). Its status may not reflect the trial's current state.
Summary
Investigators propose to conduct a multicenter, prospective, randomized, controlled, assessing the interests of an antibiotic protocol guided by the combined use of serum procalcitonin (PCT) and a broad-panel respiratory multiplex PCR (mPCR) to reduce duration of antibiotics exposure in patients with chronic obstructive pulmonary disease (COPD) hospitalized in intensive care unit (ICU) with pneumonia. The primary endpoint is the number of antibiotic-days for the treatment of pneumonia.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-03-04.
Status change: Not Yet Recruiting → Recruiting 2025-07-21
Trial Details
NCT Number NCT06301841
Lead Sponsor University Hospital, Caen
Conditions To Reduce Duration of Antibiotics Exposure in Patients With COPD Hospitalized in Intensive Care Unit With Pneumonia
Enrollment 64 participants
Start Date 2024-05-07
Primary Completion 2026-04-15 (estimated)
Study Completion 2026-07-15 (estimated)
Updated on ClinicalTrials.gov 2025-07-24