Clinical Trial

CRP and Lung Ultrasound in Respiratory Evaluation

Study acronym: PLURE
Not Yet Recruiting
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Record status
This record was last updated April 30, 2024 (before its estimated May 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
Lower respiratory tract infections (LRTIs) are one of the most common reasons for consultation in Primary Care centres. Differentiating between viral and bacterial aetiologies can be challenging, leading to inappropriate antibiotic prescribing. Lung ultrasound (LUS), an imaging test that gained particular relevance since the beginning of the SARS-CoV-2 pandemic, offers several advantages over the classic chest X-ray in detecting and monitoring LRTIs, especially when pleural involvement exists. This study aims to correlate LUS findings with capillary blood C-Reactive Protein (CRP) values in patients with LRTIs, evaluating LUS as a diagnostic tool and its impact on therapeutic decisions. The descriptive observational study, conducted from January 2024 to December 2026 in Lleida, will include LRTI patients attending Primary Care centres. By validating LUS as a rapid and non-invasive diagnostic tool, unnecessary antibiotic prescriptions can be reduced, promoting LUS as a complementary test in Primary Care consultations. This will facilitate appropriate diagnosis and treatment decisions for patients with LRTIs, enhancing the overall management of respiratory infections.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-02-28.
Trial Details
NCT Number NCT06294899
Lead Sponsor Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Conditions Primary Health Care, Lower Respiratory Tract Infection
Enrollment 202 participants
Start Date 2024-06-01
Primary Completion 2025-05-30 (estimated)
Study Completion 2028-09-01 (estimated)
Updated on ClinicalTrials.gov 2024-04-30