Clinical Trial

A Trial of Hydrus Microstent Versus Goniotomy

Recruiting
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Summary
The goal of this clinical trial is to evaluate the comparative efficacy and safety of Hydrus Microstent, incisional goniotomy, and excisional goniotomy when combined with cataract surgery in patients with mild and moderate open-angle glaucoma. The main questions it aims to answer are: * How do the intraocular pressure lowering effects of these three microinvasive glaucoma surgeries compare? * How do the safety profiles of these three microinvasive glaucoma surgeries compare? Participants will be randomized to one of these three microinvasive glaucoma surgeries in combination with cataract surgery.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-02-25; most recent amendment 2026-03-24.
Status change: Not Yet Recruiting → Recruiting 2025-03-10
Trial Details
NCT Number NCT06289491
Lead Sponsor Massachusetts Eye and Ear Infirmary
Conditions Glaucoma, Glaucoma, Open-Angle
Enrollment 243 participants
Start Date 2025-02-14
Primary Completion 2027-04 (estimated)
Study Completion 2029-04 (estimated)
Updated on ClinicalTrials.gov 2026-03-30