Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication

This randomized controlled trial aims to investigate the impact of conduction system pacing in comparison to right ventricular apical pacing on exercise capacity, as measured by peak oxygen uptake (VO2peak), in heart failure patients with indication for pacing but no compelling indication for cardiac resynchronization therapy (CRT). The mechanisms of exercise intolerance in heart failure patients influenced by conduction system pacing will be assessed.

NCT Number	NCT06278844
Lead Sponsor	University Hospital, Antwerp
Conditions	Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction, Heart Conduction Disorder
Enrollment	75 participants
Start Date	2023-12-12
Primary Completion	2026-09 (estimated)
Study Completion	2027-12 (estimated)
Updated on ClinicalTrials.gov	2024-02-26