Clinical Trial

The Combination of Adebrelimab and TP Regimen for Neoadjuvant Therapy in Patients With Stage IVB Oral Squamous Cell Carcinoma

Recruiting Phase 2
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Record status
This record was last updated May 29, 2025 (before its estimated July 31, 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this \[type of study:clinical trial\] is to \[learn about\] in \[Clinical IVB stage oral squamous cell carcinoma patients\]. The main question it aims to answer are: • \[Observing the effectiveness and safety of the combination of Adebrelimab and TP regimen in neoadjuvant therapy for clinical IVB stage oral squamous cell carcinoma patients\] Participants will \[Received treatment with Adebrelimab combined with TP regimen, followed by surgery after 2 cycles of neoadjuvant therapy. After surgery, radiotherapy and chemotherapy combined with immunotherapy were chosen based on the patient\'s condition, with a total follow-up of two years.\].
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-02-18.
Trial Details
NCT Number NCT06277791
Lead Sponsor Hospital of Stomatology, Wuhan University
Conditions Clinical IVb Stage Oral Squamous Cell Carcinomas Patients
Enrollment 35 participants
Start Date 2023-08-19
Primary Completion 2025-07-31 (estimated)
Study Completion 2026-07-31 (estimated)
Updated on ClinicalTrials.gov 2025-05-29