Clinical Trial

Differences in Speed of Recovery From Anesthesia for Intraoral Surgery

Study acronym: PSIOS
Recruiting
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Summary
The goal of this clinical trial is to compare two groups of patients going in general anesthesia for intraoral surgery, the first group TIVA with propofol and the second group inhalational with sevoflurane. The main questions it aims to answer are to asses speed and quality of recovery from general anesthesia. Participants will fill out a questionnaire to evaluate the quality of recovery from anesthesia using the QoR-40 1h, 24h, and 30 days after waking up from anesthesia in comparison to the results of the same questionnaire before surgery. Also, the investigators will perform a hand grip and bite strength test on the patients after waking up from anesthesia in the operating room, after 1 hour in the recovery room, and after 24 hours compared to preoperative values. The investigators will compare TIVA and Volatile groups to see if there are any differences in recovery seed, muscle strength recovery, postoperative nausea and vomiting, and shivering between groups.
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2024-02-16; most recent amendment 2025-12-17.
Status change: Not Yet Recruiting → Recruiting 2024-04-19
Trial Details
NCT Number NCT06275087
Lead Sponsor Clinical Hospital Centre Zagreb
Conditions Intraoral Tumor
Enrollment 42 participants
Start Date 2024-04-10
Primary Completion 2025-11-05 (estimated)
Study Completion 2026-07 (estimated)
Updated on ClinicalTrials.gov 2025-12-24