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Tumor Microenvironment in Ovarian Cancer

Study acronym: MICO
StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated February 22, 2024 (before its estimated July 2024 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
A detailed understanding of molecular mechanism of cancer genesis is fundamental to develop innovative and personalized therapies. The new frontier in biomedical research is represented by organoids, a three-dimensional cell culture system obtained from a tissue fragment that accurately reproduces the essential properties of the original tissue in vitro, which could provide a valuable model for explanation of ovarian cancers pathogenesis and will allow to predict the response to a specific therapy. With this research project, we expect to generate ovarian cancer organoids to characterize in vitro interactions and molecular pathway among tumor cells, immune cells, and resident microbiota (intratumoral bacteria and/or microbial-derived molecules).
Trial Details
NCT Number NCT06272240
Lead Sponsor University of Udine
Conditions
(from sponsor)		 Ovarian Cancer Stage III, Ovarian Cancer Stage IV
Related terms Ovarian Neoplasms
Enrollment 50 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov