Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma

A phase I clinical research study aimed at determining mechanisms that regulate airway mucosal inflammation in asthma endotypes using intranasal administration of endotoxin (lipopolysaccharide from E. coli) in healthy controls and subjects diagnosed with asthma.

NCT Number	NCT06270576
Lead Sponsor	National Jewish Health
Conditions	Asthma; Eosinophilic, Asthma
Enrollment	60 participants
Start Date	2024-04
Primary Completion	2028-04 (estimated)
Study Completion	2028-06 (estimated)
Updated on ClinicalTrials.gov	2024-02-21