Kinesiological / Dietary Supplement Intervention in Knee Osteoarthritis

The goal of this clinical trial is to assess the effectiveness of dietary supplement combined with exercise in managing knee osteoarthritis (KOA). The main questions it aims to answer are: * Is adding a dietary supplement to exercise additionally effective in managing KOA? * Is adding exercise to the dietary supplement additionally effective in managing KOA? Participants will be given in three groups: 1. Real dietary supplement alone 2. Real dietary supplement with exercise 3. Placebo dietary supplement with exercise Investigators will compare groups 1 and 2, or 2 and 3, to answer the research questions. The hypothesis is that participants who receive the dietary supplement along with exercise will experience greater reduction in pain level, improved physical function, and enhanced quality of life compared to those who receive a placebo combined with exercise or dietary supplement alone.

NCT Number	NCT06269549
Lead Sponsor	University of Primorska Collaborators: Community Healthcare Center dr. Adolf Drolc Maribor (HCM)
Conditions	Osteoarthritis, Knee
Enrollment	93 participants
Start Date	2024-03-11
Primary Completion	2026-05-31 (estimated)
Study Completion	2026-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-02-23