Clinical Trial

Targeted Plasticity Therapy for PTSD

Recruiting
View on ClinicalTrials.gov →
Summary
Objectives of this study are to provide continued safety assessment for the ReStore system, and to gain further estimates of the effect size of Vagus Nerve Stimulation (VNS) therapy with Prolonged Exposure Therapy (PE) compared to PE with placebo (sham) stimulation in participants with posttraumatic stress disorder (PTSD)
Protocol Amendment History 13 amendments
This ClinicalTrials.gov record has been amended 13 times since 2024-02-08; most recent amendment 2026-06-04.
Status change: Not Yet Recruiting → Recruiting 2024-12-15
Status change: Withheld → Not Yet Recruiting 2024-07-24
Trial Details
NCT Number NCT06266364
Lead Sponsor The University of Texas at Dallas
Collaborators: Congressionally Directed Medical Research Programs, The University of Texas Health Science Center at San Antonio
Conditions PTSD, Post Traumatic Stress Disorder
Enrollment 20 participants
Start Date 2024-12-30
Primary Completion 2027-09 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-06-08