Clinical Trial

Brain Controlled Spinal Cord Stimulation In Participants With Spinal Cord Injury For Lower Limb Rehabilitation

Study acronym: Think2Go
Active, Not Recruiting
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Summary
The purpose of this clinical study is to evaluate the preliminary safety and effectiveness of using a cortical recording device (ECoG) combined with lumbar targeted epidural electrical stimulation (EES) of the spinal cord to restore voluntary motor functions of lower limbs in participants with chronic spinal cord injury suffering from mobility impairment. The goal is to establish a direct bridge between the motor intention of the participant and the the spinal cord below the lesion, which should not only improve or restore voluntary control of legs movement and support immediate locomotion, but also promote neurological recovery when combined with neurorehabilitation.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2024-02-05; most recent amendment 2026-06-09.
Status change: Recruiting → Active, Not Recruiting 2026-06-09
Status change: Not Yet Recruiting → Recruiting 2024-09-27
Trial Details
NCT Number NCT06243952
Lead Sponsor Ecole Polytechnique Fédérale de Lausanne
Conditions Spinal Cord Injuries, Paraplegia
Enrollment 3 participants
Start Date 2024-05-03
Primary Completion 2030-07 (estimated)
Study Completion 2030-07 (estimated)
Updated on ClinicalTrials.gov 2026-07-28