Personalisation of Prosthetic Care for Lower- Limb Amputees

The global rise in lower-limb amputations is mainly due to diabetes and vascular complications. Amputations cause serious physical and psycho-social disabilities which impair locomotion and compromise patients quality of life. Biopsychosocial factors such as altered gait parameters, poor prosthetic fit, depression, fear avoidance behaviours and stigma increase the risk of individuals incurring lower back pain; the leading cause of secondary disability amongst persons with lower-limb amputation. Exploring the potential mechanistic pathways of lower back pain development is important to inform timely patient-centred programmes of care. Currently, limited information exists to inform the design of such programmes. Thus, there is a pressing need to understand the bio-behavioural, psychological, and social features of individuals with lower-limb amputation in the presence of lower back pain.

NCT Number	NCT06243549
Lead Sponsor	University of Bath Collaborators: University Hospitals Bristol and Weston NHS Foundation Trust, Portsmouth Hospitals NHS Trust
Conditions	Low Back Pain
Enrollment	30 participants
Start Date	2023-09-01
Primary Completion	2025-10 (estimated)
Study Completion	2026-10 (estimated)
Updated on ClinicalTrials.gov	2025-03-27