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The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans

Study acronym: PTSD
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 4 months later Jul 2026 → Dec 2026
See other at-risk trials from Children's Hospital Los Angeles

Record History

  1. Primary completion pushed from Jul 2026 to Dec 2026
    • Enrollment increased: 80 → 90 participants
    v5
  2. Primary completion date: Jun 2025 to Jul 2026
    • Study completion date: Jan 2026 to Jul 2027
    v4
  3. Re-verified, no change to tracked fieldsv3
  4. Start date changed from estimate of Jan 2024 to Mar 22, 2024v2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this clinical trial is to develop a new behavioral treatment for U.S. combat veterans with post-traumatic stress disorder (PTSD), very brief exposure to combat-related stimuli. The main questions it aims to answer are: 1. How does Very Brief Exposure (combat images and control everyday images) and Visible Exposure to combat stimuli affect brain activity and subjective fear ratings? 2. To what extent are participants aware of the stimuli presented and tolerating the exposures? All participants will view both very brief exposure and visible exposure to combat stimuli in the functional magnetic brain imaging (fMRI) scan. They will provide ratings of fear, awareness, and tolerability. Researchers will compare U.S. combat veterans with PTSD and healthy controls to confirm differences in brain region activation and ratings.
Trial Details
NCT Number NCT06218381
Lead Sponsor Children's Hospital Los Angeles
Conditions
(from sponsor)		 Post Traumatic Stress Disorder
Related terms Stress Disorders, Post-Traumatic
Enrollment 90 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov