Clinical Trial

Speculum Insertion During Embryo Transfer

Recruiting
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Summary
Lubrication gels are widely used in numerous gynecologic procedures in order to ease the insertion of speculum and visualize the cervix. It was shown that applying lubricating gels significantly decreases patient pain during vaginal speculum examination. While many fertility specialists use lubrication gels to insert the speculum during embryo transfer (ET), others are strongly reluctant to use gels due to concern that they might have a detrimental effect on embryos and ET success. Similar concern was prevalent regarding the use of lubrication gel during Pap-smear for detection of cervical dysplasia. However, several studies have shown that the use of small amount of water-soluble gel does not change cervical cytology. Lubrication gels might have deleterious effect on sperm motility. However, there wasn't any study examining the effect of lubricant gel on ET success. The investigators hypothesize that using a lubrication gel will not reduce the live birth rate per transfer, but decrease patient pain during procedure.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2024-01-17.
Status change: Not Yet Recruiting → Recruiting 2024-07-22
Trial Details
NCT Number NCT06210451
Lead Sponsor Wolfson Medical Center
Conditions IVF
Enrollment 416 participants
Start Date 2024-05-01
Primary Completion 2026-12-31 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2024-07-24