Clinical Trial

The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament

Recruiting Phase 2/3
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Record status
This record was last updated May 30, 2025 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.
Summary
The goal of this randomized clinical trial is to evaluate the capability of the material to exert bacterial reduction of diclofenac sodium versus of that calcium hydroxide paste when these materials are used as intracanal medications in permanent molar teeth with chronic apical periodontitis. The main question\[s\] it aims to answer are: • Will the diclofenac sodium (NSAIDs) possess antimicrobial efficacy to be used effectively as an intracanal medicament similar to that of calcium hydroxide in primary endodontic treatment? Participants will be allocated randomly into three equal groups by using computer generated randomization, according to the type of intracanal medication.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2024-01-12; most recent amendment 2025-05-26.
Trial Details
NCT Number NCT06207253
Lead Sponsor British University In Egypt
Conditions Endodontic Disease, Pulp Disease, Dental, Intracanal Medication
Enrollment 48 participants
Start Date 2025-11
Primary Completion 2025-12 (estimated)
Study Completion 2025-12 (estimated)
Updated on ClinicalTrials.gov 2025-05-30