Clinical Trial

Induction of Labor in Morbidly Obese Patients

Recruiting Early Phase 1
View on ClinicalTrials.gov →
Summary
The goal of this randomized control trial is to compare different doses of Misoprostol (25 mcg vs 50 mcg) in induction of labor (IOL) in morbidly obese patients with BMI \>40. It is known that morbid obesity is a risk factor for failed IOL and ultimately cesarean delivery (CD.) If the rates of vaginal delivery in this population can improve, then surgical morbidity can be reduced in these patients.
Protocol Amendment History 2 changes
notable Primary completion pushed: 2026-05 -> 2026-12 2026-07-30
minor Completion pushed: 2026-10 -> 2027-05 2026-07-30
Trial Details
NCT Number NCT06199154
Lead Sponsor University of Maryland, Baltimore
Conditions Morbid Obesity, Pregnancy
Enrollment 162 participants
Start Date 2024-07-15
Primary Completion 2026-12 (estimated)
Study Completion 2027-05 (estimated)
Updated on ClinicalTrials.gov 2026-07-29